Tuesday, October 21, 2014

I am bummed out.  I cannot go into the SOLO2 clinical trial.  After completing 6 rounds of Cisplatin and several trips to Princess Margaret Cancer Centre to provide blood samples and a CT Scan the researchers have told me I cannot proceed.  My CA 125 numbers have been trending up since the 4 th infusion of Cislplatin which means the cancer is active.  The trial specifically requires the CA 125 be below 35 and stable.  Mine is not.....  They are now considering me to be Platinum Resistant.

The good news is they have another trial for me.  First off, they have recommended more chemo treatement using the drug Gemcitabine pending the results from another CT Scan which is scheduled for November 7th.  If the scan shows an increase in size of cancer from the September 29th scan then chemo is probably on the table.   If the scan shows little difference then we can probably wait a bit longer and rescan in another month or 2.  I am hoping for a bit of a reprieve from chemo.  I need the time to get more healthy and strong.  I feel like a rag doll.

In addtion to the chemo they have given me information regarding a new trial that combines Gemcitabine chemo treatment with another drug which is taken orally.  The trial is called 'A Randomized Placebo-Controlled Phase II trial Compaing Gemcitabine Monotherapy to Gemcitabine in Combination with AZD1775 in Women with Recurrent, Platinum Resistant Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers.'   Quite the mouthful!

So this is where I am.  It is the usual wait and see.